Molecular weight (DA)
82kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
EFGM Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. [provided by RefSeq, Jul 2008],
Function
translation, translational elongation, mitochondrion organization, mitochondrial translation, mitochondrial translational elongation,
Gene Name
GFM1 EFG EFG1 GFM
Protein name
Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) (hEFG1)
Human protein sequence Database
Q96RP9
Mouse protein sequence database
Q8K0D5
Rat protein sequence database
Q07803
Cellular localization
Mitochondrion .
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