Molecular weight (DA)
117kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 260-340
Specificity
RBGP1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Intron retention.,similarity:Contains 1 PID domain.,similarity:Contains 1 Rab-GAP TBC domain.,subcellular location:Predominantly cytosolic but also associated with the centrosome.,subunit:Interacts with RAB6A and tubulin gamma.,
Function
function:May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Intron retention.,similarity:Contains 1 PID domain.,similarity:Contains 1 Rab-GAP TBC domain.,subcellular location:Predominantly cytosolic but also associated with the centrosome.,subunit:Interacts with RAB6A and tubulin gamma.,
Gene Name
RABGAP1 HSPC094
Protein name
Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA)
Human protein sequence Database
Q9Y3P9
Mouse protein sequence database
A2AWA9
Rat protein sequence database
Cellular localization
Cytoplasm, cytosol . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Predominantly cytosolic but also associated with the centrosome. .
Tissue expression
Brain,Mammary gland,Placenta,Testis,Umbilical cord blood,Uterus,
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