Molecular weight (DA)
23kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 50-130
Specificity
RAB17 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).[supplied by OMIM, Oct 2009],
Function
function:Might be involved in transcellular transport.,similarity:Belongs to the small GTPase superfamily. Rab family.,
Protein name
Ras-related protein Rab-17
Human protein sequence Database
Q9H0T7
Mouse protein sequence database
P35292
Rat protein sequence database
Cellular localization
Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cell projection, dendrite . May also localize at the basolateral and apical plasma membrane. In neurons, localizes to the cell body and dendritic shaft and spine. .
Tissue expression
Expressed in melanocytes (at protein level).
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