Molecular weight (DA)
105kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TSP3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
thrombospondin 3(THBS3) Homo sapiens The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011],
Function
function:Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.,similarity:Belongs to the thrombospondin family.,similarity:Contains 1 TSP C-terminal (TSPC) domain.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:Contains 4 EGF-like domains.,similarity:Contains 8 TSP type-3 repeats.,subunit:Oligomer; disulfide-linked.,
Protein name
Thrombospondin-3
Fields
>>Phagosome;>>PI3K-Akt signaling pathway;>>Focal adhesion;>>ECM-receptor interaction;>>Malaria;>>Human papillomavirus infection
Human protein sequence Database
P49746
Mouse protein sequence database
Q05895
Rat protein sequence database
Cellular localization
extracellular region,perinuclear region of cytoplasm,
Tissue expression
Lung,PCR rescued clones,Retina,Synovial membrane,
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