Molecular weight (DA)
37kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 20-100
Specificity
CCNG2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008],
Function
developmental stage:Expression levels increase through the cell cycle to peak in the mid/late-S phase and decrease during G2/M phase.,function:May play a role in growth regulation and in negative regulation of cell cycle progesssion.,induction:Activated by actinomycin-D induced DNA damage.,similarity:Belongs to the cyclin family.,similarity:Belongs to the cyclin family. Cyclin G subfamily.,tissue specificity:High levels in cerebellum, thymus, spleen and prostate. Low levels in skeletal muscle.,
Fields
>>FoxO signaling pathway;>>p53 signaling pathway
Human protein sequence Database
Q16589
Mouse protein sequence database
O08918
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
High levels in cerebellum, thymus, spleen and prostate. Low levels in skeletal muscle.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车