Molecular weight (DA)
42kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 50-130
Specificity
TSP50 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
caution:Although related to peptidase S1 family, lacks the conserved active Ser residue in position 310 which is replaced by a Thr, suggesting that it has no protease activity.,miscellaneous:DNA hypomethylation is accompanied by the expression of the gene in the testis.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Testis specific. Differentially expressed in some breast cancer tissues.,
Function
caution:Although related to peptidase S1 family, lacks the conserved active Ser residue in position 310 which is replaced by a Thr, suggesting that it has no protease activity.,miscellaneous:DNA hypomethylation is accompanied by the expression of the gene in the testis.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Testis specific. Differentially expressed in some breast cancer tissues.,
Gene Name
PRSS50 CT20 TSP50
Protein name
Probable threonine protease PRSS50 (EC 3.4.25.-) (Cancer/testis antigen 20) (Serine protease 50) (Testis-specific protease-like protein 50)
Human protein sequence Database
Q9UI38
Mouse protein sequence database
Q8BLH5
Rat protein sequence database
Cellular localization
Endoplasmic reticulum . May also localize to cytoplasmic membranes.
Tissue expression
Testis specific. Differentially expressed in some breast cancer tissues.
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