Molecular weight (DA)
12kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-50
Specificity
SPXN Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a hormone involved in modulation of cardiovascular and renal function. It has also been shown in rats to cause weight loss. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016],
Function
function:Induces contraction of stomach muscle.,tissue specificity:Expressed in submucosal layer of esophagus and stomach fundus. Expressed in brain, pancreas and kidney.,
Protein name
Spexin (NPQ)
Fields
>>Neuroactive ligand-receptor interaction
Human protein sequence Database
Q9BT56
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted. Secreted, extracellular space. Cytoplasmic vesicle, secretory vesicle. Secreted via the classical ER/Golgi-dependent pathway into the extracellular medium largely as a full-length protein without the signal peptide, and not as a hydrolyzed and amidated peptide (PubMed:19193193 and PubMed:17284679). Localized extracellularly surrounding the villous trophoblastic cells. Detected in the serum.
Tissue expression
Expressed in the type I glomic cells within the carotid body (at protein level). Expressed predominantly in pancreas, testis, kidney, brain and placenta. Expressed in submucosal layer of esophagus and stomach fundus.
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