Molecular weight (DA)
75kD
Immunogen
Synthesized peptide derived from human TBC1D15 AA range: 604-654
Specificity
This antibody detects endogenous levels of TBC1D15 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the Ras-like proteins in brain-GTPase activating protein superfamily that share a conserved Tre-2/Bub2/Cdc16 domain. The encoded protein interacts with Ras-like protein in brain 5A and may function as a regulator of intracellular trafficking. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009],
Function
function:May act as a GTPase-activating protein for Rab family protein(s).,similarity:Contains 1 Rab-GAP TBC domain.,
Other name
TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)
Fields
>>Mitophagy - animal
Human protein sequence Database
Q8TC07
Mouse protein sequence database
Q9CXF4
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Ubiquitous.
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