Molecular weight (DA)
38kD
Immunogen
Synthesized peptide derived from human F105B AA range: 284-334
Specificity
This antibody detects endogenous levels of F105B at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.17% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016],
Function
similarity:Belongs to the FAM105 family.,
Other name
Protein FAM105B
Human protein sequence Database
Q96BN8
Mouse protein sequence database
Q3UCV8
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Ovary,Prostate,
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