Molecular weight (DA)
38kD
Immunogen
Synthesized peptide derived from human SPSB3 AA range: 102-152
Specificity
This antibody detects endogenous levels of SPSB3 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.73% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
domain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,function:May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,sequence caution:Intron retention.,similarity:Belongs to the SPSB family.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 SOCS box domain.,subunit:Interacts with MET.,
Gene Name
SPSB3 C16orf31 SSB3
Other name
SPRY domain-containing SOCS box protein 3 (SSB-3)
Human protein sequence Database
Q6PJ21
Mouse protein sequence database
Q571F5
Rat protein sequence database
Cellular localization
intracellular,
Tissue expression
Brain,Eye,Hypothalamus,Testis,
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