Molecular weight (DA)
105kD
Immunogen
Synthesized peptide derived from human CE112 AA range: 475-525
Specificity
This antibody detects endogenous levels of CE112 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.234% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],
Function
sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 563.,
Other name
Centrosomal protein of 112 kDa (Coiled-coil domain-containing protein 46)
Human protein sequence Database
Q8N8E3
Mouse protein sequence database
Q5PR68
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes around spindle poles in some cells. .
Tissue expression
Lung,PCR rescued clones,Testis,Uterus,
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