Immunogen
Synthesized peptide derived from human LCE2B AA range: 31-81
Specificity
This antibody detects endogenous levels of LCE2B at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is one of the at least 20 genes expressed during epidermal differentiation and located on chromosomal band 1q21. This gene is involved in epidermal differentiation, and it is expressed at high levels in normal and psoriatic skin, but not in cultured keratinocytes or in any other tested cell types or tissues. [provided by RefSeq, Jul 2008],
Function
function:Precursors of the cornified envelope of the stratum corneum.,induction:By calcium and UVB.,miscellaneous:Belongs to the LCE cluster present on 1q21.,similarity:Belongs to the LCE family.,tissue specificity:Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.,
Gene Name
LCE2B LEP10 SPRL1B XP5
Human protein sequence Database
O14633
Mouse protein sequence database
Rat protein sequence database
Cellular localization
cornified envelope,cytoplasm,
Tissue expression
Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.
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