Immunogen
Synthesized peptide derived from human FGD3 AA range: 69-119
Specificity
This antibody detects endogenous levels of FGD3 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 FYVE-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 2 PH domains.,
Fields
>>Regulation of actin cytoskeleton
Human protein sequence Database
Q5JSP0
Mouse protein sequence database
O88842
Rat protein sequence database
Cellular localization
Cytoplasm . Cytoplasm, cytoskeleton .