Immunogen
Synthesized peptide derived from human TYY2 AA range: 9-59
Specificity
This antibody detects endogenous levels of TYY2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a transcription factor that includes several Kruppel-like zinc fingers in its C-terminal region. It possesses both activation and repression domains, and it can therefore have both positive and negative effects on the transcription of target genes. This gene has an intronless coding region, and it appears to have arisen by retrotransposition of the related YY1 transcription factor gene, which is located on chromosome 14. [provided by RefSeq, May 2010],
Function
function:Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes. May antagonize YY1 and function in development and differentiation.,miscellaneous:The gene encoding this protein appears to have arisen by retrotransposition of the YY1 gene in placental mammals. It is encoded by a single exon found in an intron of the gene Mbtps2.,similarity:Belongs to the YY transcription factor family.,similarity:Contains 4 C2H2-type zinc fingers.,tissue specificity:Expressed in kidney, liver, spleen and testis but not in colon.,
Human protein sequence Database
O15391
Mouse protein sequence database
Q3TTC2
Rat protein sequence database
P0C6P6
Cellular localization
Nucleus .
Tissue expression
Expressed in kidney, liver, spleen and testis but not in colon.
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