Immunogen
Synthesized peptide derived from human PPAC2 AA range: 145-195
Specificity
This antibody detects endogenous levels of PPAC2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid.,similarity:Belongs to the PA-phosphatase related phosphoesterase family.,tissue specificity:Widely expressed. Expressed in most organs, in particular gastrointestinal organs, spleen, placenta, kidney, thymus and brain.,
Human protein sequence Database
Q8IY26
Mouse protein sequence database
Q9D4F2
Rat protein sequence database
Q66H88
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Nucleus envelope . Nucleus inner membrane .
Tissue expression
Widely expressed. Expressed in most organs, in particular gastrointestinal organs, spleen, placenta, kidney, thymus and brain.