Immunogen
Synthesized peptide derived from human INCA1 AA range: 10-60
Specificity
This antibody detects endogenous levels of INCA1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
PTM:Phosphorylated when part of a complex with CCNA1 and CDK2. Strongly phosphorylated by CDK2 on its C-terminal region spanning amino acid 149-221. Less intensively phosphorylated by CDK2 on its first 75 amino acid residues.,similarity:Belongs to the INCA family.,subunit:Interacts with CCNA1. Identified in a complex with CCNA1 and CDK2.,tissue specificity:Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors.,
Human protein sequence Database
Q0VD86
Mouse protein sequence database
Q6PKN7
Rat protein sequence database
Cellular localization
Nucleus . Cytoplasm .
Tissue expression
Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors (PubMed:15159402). Down-regulated in bone marrow cells in acute myeloid and lymphoid leukemia patients as compared with normal bone marrow cells (PubMed:21540187).
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