Immunogen
Synthesized peptide derived from human TM138 AA range: 75-125
Specificity
This antibody detects endogenous levels of TM138 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a multi-pass transmembrane protein. Reduced expression of this gene in mouse fibroblasts causes short cilia and failure of ciliogenesis. Expression of this gene is tightly coordinated with expression of the neighboring gene TMEM216. Mutations in this gene are associated with the autosomal recessive neurodevelopmental disorder Joubert Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012],
Function
similarity:Belongs to the TMEM138 family.,
Gene Name
TMEM138 HSPC196 HSPC198
Human protein sequence Database
Q9NPI0
Mouse protein sequence database
Q9D6G5
Rat protein sequence database
B1WBM3
Cellular localization
Vacuole membrane ; Multi-pass membrane protein . Cell projection, cilium . Localizes to vesicles en route to the base of cilium.
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