Immunogen
Synthesized peptide derived from human PYDC1 AA range: 25-75
Specificity
This antibody detects endogenous levels of PYDC1 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1：50-200. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.,PTM:Phosphorylated.,similarity:Contains 1 DAPIN domain.,subunit:Interacts with PYCARD/ASC.,tissue specificity:Predominantly expressed in monocytes, macrophages and granulocytes.,
Gene Name
PYDC1 ASC2 ASCI POP1 PYC1
Fields
>>NOD-like receptor signaling pathway
Human protein sequence Database
Q8WXC3
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm . Recruited to specks formed by PYCARD within the cytoplasm. .
Tissue expression
Predominantly expressed in monocytes, macrophages and granulocytes.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车