Immunogen
Synthesized peptide derived from human NIPA2 AA range: 175-225
Specificity
This antibody detects endogenous levels of NIPA2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a possible magnesium transporter. This gene is located adjacent to the imprinted domain in the Prader-Willi syndrome deletion region of chromosome 15. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 7 and 21.[provided by RefSeq, May 2010],
Function
similarity:Belongs to the NIPA family.,tissue specificity:Widely expressed.,
Human protein sequence Database
Q8N8Q9
Mouse protein sequence database
Q9JJC8
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein . Early endosome . Recruited to the cell membrane in response to low extracellular magnesium. .
Tissue expression
Widely expressed.