Immunogen
Synthesized peptide derived from human SIA7B AA range: 219-269
Specificity
This antibody detects endogenous levels of SIA7B at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting (Samyn-Petit et al., 2000 [PubMed 10742600]).[supplied by OMIM, Mar 2008],
Function
catalytic activity:CMP-N-acetylneuraminate + glycano-beta-D-galactosyl-1,3-(N-acetyl-D-galactosaminyl)-glycoprotein = CMP + glycano-beta-D-galactosyl-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein.,online information:GlycoGene database,online information:ST6GalNAc II,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 29 family.,tissue specificity:Expressed in skeletal muscle, heart, kidney, placenta, lung and leukocytes.,
Gene Name
ST6GALNAC2 SIAT7B SIATL1 STHM
Fields
>>Mucin type O-glycan biosynthesis;>>Metabolic pathways
Human protein sequence Database
Q9UJ37
Mouse protein sequence database
P70277
Rat protein sequence database
Cellular localization
Golgi apparatus membrane ; Single-pass type II membrane protein .
Tissue expression
Expressed in skeletal muscle, heart, kidney, placenta, lung and leukocytes.