Immunogen
Synthesized peptide derived from human CHM2B AA range: 53-103
Specificity
This antibody detects endogenous levels of human CHM2B
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2)
Fields
>>Endocytosis;>>Necroptosis;>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases
Human protein sequence Database
Q9UQN3
Mouse protein sequence database
Q8BJF9
Rat protein sequence database
Cellular localization
Cytoplasm, cytosol . Late endosome membrane ; Peripheral membrane protein .
Tissue expression
Widely expressed. Expressed in brain, heart, skeletal muscle, spleen, kidney, liver, small intestine, pancreas, lung, placenta and leukocytes. In brain, it is expressed in cerebellum, cerebral cortex, medulla, spinal chord, occipital lobe, frontal lobe, temporal lobe and putamen.
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