Immunogen
Synthesized peptide derived from human STOM AA range: 38-88
Specificity
This antibody detects endogenous levels of human STOM
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
STOM BND7 EPB72
Protein name
Erythrocyte band 7 integral membrane protein (Protein 7.2b) (Stomatin)
Human protein sequence Database
P27105
Mouse protein sequence database
P54116
Rat protein sequence database
Cellular localization
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Cell membrane ; Lipid-anchor ; Cytoplasmic side . Membrane raft . Melanosome . Cytoplasmic vesicle . Localizes to juxtanuclear structure probably derived from the Golgi apparatus (PubMed:9243190). Colocalizes with cortical actin microfilaments at small plasma membrane protrusions (PubMed:9243190). Associates with alpha-granular lipid rafts (PubMed:12130500). Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles (PubMed:12130500). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). .
Tissue expression
Detected in erythrocytes (at protein level). Widely expressed.
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