Immunogen
Synthesized peptide derived from human RN19B AA range: 272-322
Specificity
This antibody detects endogenous levels of human RN19B
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
RNF19B IBRDC3 NKLAM
Protein name
E3 ubiquitin-protein ligase RNF19B (EC 6.3.2.-) (IBR domain-containing protein 3) (Natural killer lytic-associated molecule) (RING finger protein 19B)
Human protein sequence Database
Q6ZMZ0
Mouse protein sequence database
A2A7Q9
Rat protein sequence database
Cellular localization
Cytoplasmic granule membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Tissue expression
Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells (PubMed:10438909). Present in natural killer cells (at protein level) (PubMed:10912506). Ubiquitously expressed with high expression in testis (PubMed:27485036).