Immunogen
Synthesized peptide derived from human SETD8 AA range: 282-332
Specificity
This antibody detects endogenous levels of human SETD8
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
SETD8 KMT5A PRSET7 SET07 SET8
Protein name
N-lysine methyltransferase SETD8 (EC 2.1.1.-) (H4-K20-HMTase SETD8) (Histone-lysine N-methyltransferase SETD8) (EC 2.1.1.43) (Lysine N-methyltransferase 5A) (PR/SET domain-containing protein 07) (PR-S
Fields
>>Lysine degradation;>>Metabolic pathways
Human protein sequence Database
Q9NQR1
Mouse protein sequence database
Q2YDW7
Rat protein sequence database
Cellular localization
Nucleus. Chromosome. Specifically localizes to mitotic chromosomes. Colocalized with SIRT2 at mitotic foci. Associates with chromosomes during mitosis; association is increased in a H(2)O(2)-induced oxidative stress-dependent manner. Associates with silent chromatin on euchromatic arms. Not associated with constitutive heterochromatin.