Molecular weight (DA)
57kD
Immunogen
Recombinant Protein of ATG13
Specificity
The antibody detects endogenous ATG13 protein
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-300. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is an autophagy factor and a target of the TOR kinase signaling pathway. The encoded protein is essential for autophagosome formation and mitophagy. [provided by RefSeq, Oct 2016],
Function
autophagic vacuole formation, autophagy, vacuole organization, cellular response to starvation, response to extracellular stimulus, macroautophagy, response to nutrient levels, cellular response to extracellular stimulus, cellular response to nutrient levels, cellular response to stress, response to starvation,
Protein name
Autophagy-related protein 13
Other name
Autophagy-related protein 13
Fields
>>Autophagy - other;>>Autophagy - animal;>>Longevity regulating pathway;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases
Human protein sequence Database
O75143
Mouse protein sequence database
Q91YI1
Rat protein sequence database
Cellular localization
Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .
Tissue expression
Amygdala,Brain,
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