Immunogen
Synthesized peptide derived from human BCLAF1 (Phospho-Ser531)
Specificity
This antibody detects endogenous levels of BCLAF1 (Phospho-Ser531) at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, and 0.208% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Function
function:Death-promoting transcriptional repressor.,sequence caution:Contaminating sequence. Potential poly-A sequence.,subunit:Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA.,tissue specificity:Ubiquitous.,
Gene Name
BCLAF1 BTF KIAA0164
Protein name
BCLAF1 (Phospho-Ser531)
Other name
Bcl-2-associated transcription factor 1 (Btf)
Human protein sequence Database
Q9NYF8
Mouse protein sequence database
Q8K019
Rat protein sequence database
Cellular localization
Cytoplasm. Nucleus. Nucleus speckle . Nucleus, nucleoplasm .
Tissue expression
Ubiquitous.
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