Molecular weight (DA)
21kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PGLYRP1. AA range:131-180
Specificity
PGLYRP1 Polyclonal Antibody detects endogenous levels of PGLYRP1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
PGLYRP1 (Peptidoglycan Recognition Protein 1) is a Protein Coding gene. Among its related pathways are TNF Signaling (sino). GO annotations related to this gene include peptidoglycan binding and N-acetylmuramoyl-L-alanine amidase activity. An important paralog of this gene is PGLYRP4.
Function
peptidoglycan metabolic process, polysaccharide catabolic process, polysaccharide metabolic process, aminoglycan metabolic process, aminoglycan catabolic process, glycosaminoglycan catabolic process, defense response, immune response, behavior, rhythmic behavior, circadian rhythm, macromolecule catabolic process, peptidoglycan catabolic process, detection of external stimulus, detection of biotic stimulus, response to bacterium, detection of bacterium,carbohydrate catabolic process, circadian sleep/wake cycle process, glycosaminoglycan metabolic process, defense response to bacterium, circadian sleep/wake cycle, regulation of circadian sleep/wake cycle, regulation of circadian rhythm, innate immune response, regulation of circadian sleep/wake cycle, sleep, rhythmic process, circadian behavior,regulation of behavior, defense response to Gram-positive bacterium, detection of stimulus,
Protein name
Peptidoglycan recognition protein 1
Other name
PGLYRP1; PGLYRP; PGRP; TNFSF3L; SBBI68; Peptidoglycan recognition protein 1; Peptidoglycan recognition protein short; PGRP-S
Human protein sequence Database
O75594
Mouse protein sequence database
O88593
Rat protein sequence database
Cellular localization
Secreted . Cytoplasmic granule .
Tissue expression
Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.
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