Immunogen
Synthetic peptide from human protein at AA range: 1-60
Specificity
The antibody detects endogenous Cytoglobin
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012],
Function
function:May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.,similarity:Belongs to the globin family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine.,
Protein name
Cytoglobin (Histoglobin) (HGb) (Stellate cell activation-associated protein)
Other name
Cytoglobin (Histoglobin;HGb;Stellate cell activation-associated protein)
Human protein sequence Database
Q8WWM9
Mouse protein sequence database
Q9CX80
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine.