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INT8 rabbit pAb

Refer to | for labeled antibodies

Specification

BYab-11002

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Product introduction Experimental scheme Citation Related products

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Host
Reactiveness
Use
Molecular weight (DA)
Immunogen
Synthesized peptide derived from human INT8 AA range: 346-396
Specificity
This antibody detects endogenous levels of INT8 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Background
This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012],
Function
function:Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.,similarity:Contains 4 TPR repeats.,subunit:Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12.,
Gene Name
INTS8 C8orf52
Protein name
INT8
Abbreviation
INT8
Other name
Fields
Human gene ID
55656
Human protein sequence Database
Q75QN2
Mouse gene ID
72656
Mouse protein sequence database
Q80V86
Rat gene ID
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Storage
-20°C/1 year

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INT8 rabbit pAb

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