Immunogen
Synthesized peptide derived from human LRC26 AA range: 163-213
Specificity
This antibody detects endogenous levels of LRC26 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
similarity:Contains 6 LRR (leucine-rich) repeats.,subcellular location:Although predicted to be a single-pass type I membrane protein, this protein localizes to the cytoplasm when expressed at high levels (PubMed:15164053).,tissue specificity:Expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer.,
Human protein sequence Database
Q2I0M4
Mouse protein sequence database
Q91W20
Rat protein sequence database
Q6P7C4
Cellular localization
Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Localizes to the cytoplasm when expressed at high levels. .
Tissue expression
Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer. Isoform 2 is expressed in cancer cell lines.
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