Immunogen
Synthesized peptide derived from human HMBX1 AA range: 169-219
Specificity
This antibody detects endogenous levels of HMBX1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Putative transcription factor .,similarity:Contains 1 homeobox DNA-binding domain.,
Human protein sequence Database
Q6NT76
Mouse protein sequence database
Q8BJA3
Rat protein sequence database
Cellular localization
Nucleus . Cytoplasm . Chromosome, telomere . Nucleus, Cajal body . Nucleus, PML body . Predominantly detected in cytoplasm (PubMed:16825764, PubMed:19728927). Localizes in a dynamic manner to actively processed telomeres (PubMed:23685356). Localizes to the periphery of Cajal bodies (PubMed:23685356). Associates with PML nuclear bodies in telomerase-negative cells (PubMed:23813958). .; [Isoform 5]: Nucleus . Cytoplasm .
Tissue expression
Ubiquitous. Detected in pancreas, brain, spleen, placenta, prostate, thymus, liver, heart, bone marrow, skeletal muscle, stomach, uterus, testis, kidney, ovary, colon, lung, cardiac muscle and thyroid gland.
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