Immunogen
Synthesized peptide derived from human TBCD1 AA range: 716-766
Specificity
This antibody detects endogenous levels of TBCD1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).[supplied by OMIM, Mar 2008],
Function
function:May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues.,similarity:Contains 1 PID domain.,similarity:Contains 1 Rab-GAP TBC domain.,
Gene Name
TBC1D1 KIAA1108
Fields
>>AMPK signaling pathway
Human protein sequence Database
Q86TI0
Mouse protein sequence database
Q60949
Rat protein sequence database
Cellular localization
Nucleus .
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