Immunogen
Synthesized peptide derived from human NUDT6 AA range: 225-275
Specificity
This antibody detects endogenous levels of NUDT6 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Function
miscellaneous:This protein is coded from a FGF2 (BFGF) gene antisense transcript.,similarity:Belongs to the Nudix hydrolase family.,
Human protein sequence Database
P53370
Mouse protein sequence database
Q8CH40
Rat protein sequence database
P70563
Cellular localization
Cytoplasm. Nucleus. Mitochondrion. Subcellular location may vary between isoforms.
Tissue expression
Detected in liver, kidney and esophagus (at protein level). Ubiquitous.
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