Immunogen
Synthesized peptide derived from human FNDC1 AA range: 988-1038
Specificity
This antibody detects endogenous levels of FNDC1 at Human/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
caution:It is uncertain whether Met-1 or Met-53 is the initiator.,function:May be an activator of G protein signaling.,induction:By TGF-beta present in the melanoma cell conditioned medium (MCCM).,similarity:Contains 5 fibronectin type-III domains.,tissue specificity:Almost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis.,
Gene Name
FNDC1 FNDC2 KIAA1866 MEL4B3
Human protein sequence Database
Q4ZHG4
Mouse protein sequence database
Rat protein sequence database
Q2Q0I9
Cellular localization
Secreted .
Tissue expression
Almost absent from healthy skin; especially in epidermal keratinocytes, skin fibroblasts or endothelial cells and is barely detectable in benign melanocytic naevi. Expressed in the stroma close to skin tumors, in the tumor cells themselves and in the epidermis of psoriasis.
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