Immunogen
Synthesized peptide derived from human SDC3 AA range: 131-181
Specificity
This antibody detects endogenous levels of SDC3 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009],
Function
function:Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.,PTM:O-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules.,similarity:Belongs to the syndecan proteoglycan family.,tissue specificity:Expressed in the nervous system, the adrenal gland, and the spleen.,
Fields
>>Cell adhesion molecules
Human protein sequence Database
O75056
Mouse protein sequence database
Q64519
Rat protein sequence database
P33671
Cellular localization
Cell membrane; Single-pass type I membrane protein.
Tissue expression
Expressed in the nervous system, the adrenal gland, and the spleen.
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