Immunogen
Synthesized peptide derived from human MOT10 AA range: 163-213
Specificity
This antibody detects endogenous levels of MOT10 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.[supplied by OMIM, Apr 2004],
Function
function:Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells.,PTM:Not N-glycosylated.,similarity:Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.,tissue specificity:Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart.,
Gene Name
SLC16A10 MCT10 TAT1
Fields
>>Thyroid hormone signaling pathway;>>Protein digestion and absorption
Human protein sequence Database
Q8TF71
Mouse protein sequence database
Q3U9N9
Rat protein sequence database
Q91Y77
Cellular localization
Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane .
Tissue expression
Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart.
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