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EIF3I rabbit pAb

Refer to | for labeled antibodies

Specification

BYab-11506

  • 50UL $180 100UL $255
  • Delivery: In Stock

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Host
Reactiveness
Use
Molecular weight (DA)
Immunogen
Synthesized peptide derived from human EIF3I AA range: 100-150
Specificity
This antibody detects endogenous levels of EIF3I at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Background
Function
function:Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.,mass spectrometry: PubMed:17322308,mass spectrometry: PubMed:18599441,PTM:Phosphorylated by TGF-beta type II receptor.,similarity:Belongs to the eIF-3 subunit I family.,similarity:Contains 5 WD repeats.,subunit:Component of the eukaryotic
Gene Name
EIF3I EIF3S2 TRIP1
Protein name
EIF3I
Abbreviation
EIF3I
Other name
Fields
Human gene ID
8668
Human protein sequence Database
Q13347
Mouse gene ID
54709
Mouse protein sequence database
Q9QZD9
Rat gene ID
682390
Rat protein sequence database
B0BNA7
Cellular localization
Cytoplasm .
Tissue expression
Storage
-20°C/1 year

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EIF3I rabbit pAb

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