Immunogen
Synthesized peptide derived from human TM9S4 AA range: 315-365
Specificity
This antibody detects endogenous levels of TM9S4 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
similarity:Belongs to the nonaspanin (TM9SF) family.,
Gene Name
TM9SF4 KIAA0255
Human protein sequence Database
Q92544
Mouse protein sequence database
Q8BH24
Rat protein sequence database
Q4KLL4
Cellular localization
Membrane ; Multi-pass membrane protein . Golgi apparatus . Early endosome .
Tissue expression
Highly expressed in metastatic melanoma cells whereas it is undetectable in primary melanoma cells, healthy skin tissues and peripheral blood lymphocytes. Expressed in CD34(+) hematopoietic progenitor cells and during monocyte and granulocyte differentiation. Overexpressed in acute myeloid leukemia, in particular in those displaying granulocytic differentiation (at protein level).