Immunogen
Synthesized peptide derived from human PCLI1 AA range: 144-194
Specificity
This antibody detects endogenous levels of PCLI1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Increases proliferation of preadipocytes without affecting adipocytic differentiation.,induction:Up-regulated in fat of obese subjects.,polymorphism:Some sequences seem to have a duplication of exon 2.,similarity:Contains 1 PID domain.,subunit:Found in a complex with PID1/PCLI1, LRP1 and CUBNI. Interacts with LRP1 and CUBN.,tissue specificity:Expressed in subcutaneous fat, heart, skeletal muscle, brain, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocyte.,
Gene Name
PID1 NYGGF4 PCLI1 HMFN2073
Human protein sequence Database
Q7Z2X4
Mouse protein sequence database
Q3UBG2
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Expressed in subcutaneous fat, heart, skeletal muscle, brain, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocyte.
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