Immunogen
Synthesized peptide derived from human ARMC9 AA range: 713-763
Specificity
This antibody detects endogenous levels of ARMC9 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
similarity:Contains 1 LisH domain.,tissue specificity:Strongly expressed in most melanomas and melanocytes. Weakly expressed in the testis.,
Human protein sequence Database
Q7Z3E5
Mouse protein sequence database
Q9D2I5
Rat protein sequence database
A1A5P5
Cellular localization
Cytoplasm, cytoskeleton, cilium basal body . Cell projection, cilium . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localized to the proximal region in cilia. Stimulation of Hh signaling leads to redistribution of ARMC9 toward the ciliary tip within 6 hours, follow by a gradual return to its original proximal location (By similarity). Localizes to the daughter centriole of the primary cilium in RPE1 cells (PubMed:28625504). .
Tissue expression
Strongly expressed in most melanomas and melanocytes. Weakly expressed in the testis.