Immunogen
Synthesized peptide derived from human SYFA AA range: 331-381
Specificity
This antibody detects endogenous levels of SYFA at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a product which is similar to the catalytic subunit of prokaryotic and Saccharomyces cerevisiae phenylalanyl-tRNA synthetases (PheRS). This gene product has been shown to be expressed in a tumor-selective and cell cycle stage- and differentiation-dependent manner, the first member of the tRNA synthetase gene family shown to exhibit this type of regulated expression [provided by RefSeq, Jul 2008],
Function
catalytic activity:ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).,similarity:Belongs to the class-II aminoacyl-tRNA synthetase family.,similarity:Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 2 subfamily.,subunit:Tetramer of two alpha and two beta chains.,
Gene Name
FARSA FARS FARSL FARSLA
Fields
>>Aminoacyl-tRNA biosynthesis
Human protein sequence Database
Q9Y285
Mouse protein sequence database
Q8C0C7
Rat protein sequence database
Q505J8
Cellular localization
Cytoplasm .
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