Immunogen
Synthesized peptide derived from human IRX5 AA range: 64-114
Specificity
This antibody detects endogenous levels of IRX5 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the iroquois homeobox gene family, which are involved in several embryonic developmental processes. Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation, and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
Function
similarity:Belongs to the TALE/IRO homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
Gene Name
IRX5 IRX2A IRXB2
Human protein sequence Database
P78411
Mouse protein sequence database
Q9JKQ4
Rat protein sequence database
Cellular localization
Nucleus .
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