Immunogen
Synthesized peptide derived from human PMM1 AA range: 18-68
Specificity
This antibody detects endogenous levels of PMM1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008],
Function
catalytic activity:Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.,function:Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.,pathway:Nucleotide-sugar biosynthesis; GDP-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.,similarity:Belongs to the eukaryotic PMM family.,tissue specificity:Strong expression in liver, heart, brain, and pancreas; lower expression in skeletal muscle.,
Fields
>>Fructose and mannose metabolism;>>Amino sugar and nucleotide sugar metabolism;>>Metabolic pathways;>>Biosynthesis of cofactors;>>Biosynthesis of nucleotide sugars
Human protein sequence Database
Q92871
Mouse protein sequence database
O35621
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Strong expression in liver, heart, brain, and pancreas; lower expression in skeletal muscle.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车