Immunogen
Synthesized peptide derived from human ALG13 AA range: 69-119
Specificity
This antibody detects endogenous levels of ALG13 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],
Function
catalytic activity:UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N'-diacetylchitobiosyl-diphosphodolichol.,function:Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.,online information:GlycoGene database,similarity:Belongs to the glycosyltransferase 28 family.,subunit:Heterodimer with ALG14 to form a functional enzyme.,
Gene Name
ALG13 CXorf45 GLT28D1 MDS031
Fields
>>N-Glycan biosynthesis;>>Various types of N-glycan biosynthesis;>>Metabolic pathways
Human protein sequence Database
Q9NP73
Mouse protein sequence database
Q9D8C3
Rat protein sequence database
Q5I0K7
Cellular localization
[Isoform 2]: Endoplasmic reticulum . Could be recruited to the cytosolic face of the endoplasmic reticulum membrane through its interaction with ALG14.
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