Immunogen
Synthesized peptide derived from human DPOLN AA range: 35-85
Specificity
This antibody detects endogenous levels of DPOLN at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a DNA polymerase type-A family member. The encoded protein plays a role in DNA repair and homologous recombination. This gene shares its 5' exons with some transcripts from overlapping GeneID: 79441, which encodes an augmentin-like protein complex subunit. [provided by RefSeq, Dec 2014],
Function
alternative products:Additional isoforms seem to exist,catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,similarity:Belongs to the DNA polymerase type-A family.,tissue specificity:Highly expressed in testis and heart. Weakly expressed in skeletal muscle.,
Fields
>>Fanconi anemia pathway
Human protein sequence Database
Q7Z5Q5
Mouse protein sequence database
Q7TQ07
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Highly expressed in testis and heart. Weakly expressed in skeletal muscle.