Immunogen
Synthesized peptide derived from human GDPD1 AA range: 247-297
Specificity
This antibody detects endogenous levels of GDPD1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the glycerophosphodiester phosphodiesterase family of enzymes that catalyze the hydrolysis of deacylated glycerophospholipids to glycerol phosphate and alcohol. The encoded protein is localized to the cytoplasm and concentrates near the perinuclear region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
Function
similarity:Belongs to the glycerophosphoryl diester phosphodiesterase family.,similarity:Contains 1 GDPD domain.,tissue specificity:Detected in placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood leukocytes.,
Fields
>>Ether lipid metabolism;>>Metabolic pathways
Human protein sequence Database
Q8N9F7
Mouse protein sequence database
Q9CRY7
Rat protein sequence database
Q0VGK4
Cellular localization
Cytoplasm . Membrane ; Multi-pass membrane protein . Cytoplasm, perinuclear region . Endoplasmic reticulum . Concentrated at the perinuclear region and the cell periphery (PubMed:18991142). .
Tissue expression
Widely expressed with high expression level in testis.