Immunogen
Synthesized peptide derived from human ANR27 AA range: 206-256
Specificity
This antibody detects endogenous levels of ANR27 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:May be a Rab21 guanine exchange factor and regulate endosome dynamics.,similarity:Contains 1 VPS9 domain.,similarity:Contains 11 ANK repeats.,subcellular location:Mainly localized to early endosomes in the perinuclear region.,subunit:Interacts with RAB21 and RAB5, with a strong preference for RAB21.,
Gene Name
ANKRD27 PP12899
Human protein sequence Database
Q96NW4
Mouse protein sequence database
Q3UMR0
Rat protein sequence database
Cellular localization
Early endosome . Late endosome . Cytoplasmic vesicle membrane . Lysosome . Cell membrane . Melanosome . Colocalizes with VAMP7 in transport vesicles in the shaft of hippocampal neurons (By similarity). .