Immunogen
Synthesized peptide derived from human TSLP AA range: 91-140
Specificity
This antibody detects endogenous levels of Human TSLP
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
function:Cytokine that induces the release of T cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.,induction:Released by primary epithelial cells in response to certain microbial products, physical injury, or inflammatory cytokines.,subunit:Interacts with a receptor composed of CRLF2 and IL7R.,tissue specificity:Expressed in a number of tissues including heart, liver and prostate.,
Other name
Thymic stromal lymphopoietin
Fields
>>Cytokine-cytokine receptor interaction;>>JAK-STAT signaling pathway
Human protein sequence Database
Q969D9
Mouse protein sequence database
Q9JIE6
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva.
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