Immunogen
The antiserum was produced against synthesized peptide derived from human TRAK2. AA range:430-480
Specificity
GRIF-1 Polyclonal Antibody detects endogenous levels of GRIF-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
PTM:O-glycosylated.,similarity:Contains 1 HAP1 N-terminal domain.,subunit:Interacts with GABA-A receptor and O-GlcNAc transferase (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.,tissue specificity:Widely expressed, with highest expression in heart.,
Function
PTM:O-glycosylated.,similarity:Contains 1 HAP1 N-terminal domain.,subunit:Interacts with GABA-A receptor and O-GlcNAc transferase (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.,tissue specificity:Widely expressed, with highest expression in heart.,
Protein name
Trafficking kinesin-binding protein 2
Other name
TRAK2; ALS2CR3; KIAA0549; Trafficking kinesin-binding protein 2; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein
Fields
>>GABAergic synapse
Human protein sequence Database
O60296
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm . Early endosome . Mitochondrion . Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity). .
Tissue expression
Widely expressed, with highest expression in heart.