Molecular weight (DA)
112kD
Immunogen
Synthesized peptide derived from human EPHA7 (Phospho Tyr608)
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat EPHA7 (Phospho Tyr608)
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,subunit:Interacts with PRKCABP and GRIP1.,tissue specificity:Widely expressed.,
Function
cell morphogenesis, cell morphogenesis involved in differentiation, morphogenesis of a branching structure, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell motion, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, axonogenesis, axon guidance, regulation of cell death, positive regulation of cell death, phosphorylation, cell projection organization, neuron differentiation, neuron projection development,retinal ganglion cell axon guidance, cellular component morphogenesis, cell part morphogenesis, regulation of apoptosis, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, regulation of neuron apoptosis, positive regulation of neuron apoptosis, neuron developme
Gene Name
EPHA7 EHK3 HEK11
Protein name
EPHA7 (Phospho Tyr608)
Other name
Ephrin type-A receptor 7 (EC 2.7.10.1;EPH homology kinase 3;EHK-3;EPH-like kinase 11;EK11;hEK11)
Human protein sequence Database
Q15375
Mouse protein sequence database
Q61772
Rat protein sequence database
P54759
Cellular localization
Cell membrane ; Single-pass type I membrane protein .
Tissue expression
Widely expressed.
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